Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.63 |
| ▸ | GHSR | Q92847 | 6/20 | 0.58 |
| ▸ | NUDT15 | Q9NV35 | 1/20 | 0.54 |
| ▸ | F10 | P00742 | 5/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | FASN | P49327 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5327115 | 0.83 | GHSR (0.50) | ATMGHSRNUDT15F10L3MBTL1 | |
| SCHEMBL5330111 | 0.83 | ATM (0.54) | ATMF10L3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL5326524 | 0.82 | L3MBTL1 (0.54) | ATMGHSRNUDT15F10L3MBTL1 | |
| SCHEMBL5193868 | 0.82 | ATM (0.71) | ATMF10L3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL5733762 | 0.82 | F10 (0.72) | ATMF10L3MBTL1SMN1; SMN2LMNA | |
| Hydrochloric Acid SCHEMBL6195419 | 0.81 | ATM (0.69) | ATMF10L3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL5324846 | 0.81 | HRH3 (0.54) | ATMGHSRNUDT15F10L3MBTL1 | |
| SCHEMBL6305660 | 0.80 | ATM (0.68) | ATMF10L3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL6734937 | 0.80 | ATM (0.67) | ATMF10L3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL6304930 | 0.79 | F10 (0.69) | ATMF10SMN1; SMN2LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007008145-A1 | HETEROCYCLIC SULFONAMIDE DERIVATIVES AS INHIBITORS OF FACTOR XA | ASTRAZENECA AB (SE) | 2007-01-18 | — | — | WO | claimed |
| WO-2007008145-A1 | HETEROCYCLIC SULFONAMIDE DERIVATIVES AS INHIBITORS OF FACTOR XA | ASTRAZENECA AB (SE) | 2007-01-18 | — | — | WO | disclosed |