Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 10/20 | 0.54 |
| ▸ | RORC | P51449 | 8/20 | 0.54 |
| ▸ | THRA | P10827 | 5/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3221389 | 0.86 | THRB (0.57) | THRBRORCTHRACYP2D6 | |
| SCHEMBL16495807 | 0.81 | THRB (0.54) | THRBRORCTHRA | |
| SCHEMBL3228615 | 0.80 | THRB (0.51) | THRBRORCTHRA | |
| SCHEMBL3229107 | 0.79 | THRB (0.52) | THRBRORCTHRACYP2D6 | |
| SCHEMBL16496559 | 0.78 | THRB (0.54) | THRBRORCTHRACYP2D6 | |
| SCHEMBL16496560 | 0.78 | THRB (0.54) | THRBRORCTHRACYP2D6 | |
| SCHEMBL22959356 | 0.76 | RORC (0.67) | THRBRORCTHRACYP2D6 | |
| SCHEMBL22959122 | 0.74 | RORC (0.61) | THRBRORCTHRA | |
| SCHEMBL11251015 | 0.74 | CYP2D6 (0.59) | CYP2D6 | |
| SCHEMBL282532 | 0.74 | THRB (0.50) | THRBRORCTHRACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007132475-A1 | SELECTIVE TR-BETA 1 AGONIST | CADILA HEALTHCARE LIMITED (IN) | 2007-11-22 | — | — | WO | disclosed |