Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 16/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RXRA | P19793 | 2/20 | 0.36 |
| ▸ | RXRB | P28702 | 2/20 | 0.36 |
| ▸ | RXRG | P48443 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL621034 | 0.90 | PARP1 (0.40) | PARP1KDM4ERXRARXRBRXRG | |
| SCHEMBL5328082 | 0.82 | PARP1 (0.53) | PARP1KDM4E | |
| SCHEMBL5328612 | 0.81 | PARP1 (0.39) | PARP1KDM4EMAPT | |
| SCHEMBL3950495 | 0.81 | ALDH1A1 (0.49) | PARP1KDM4EMAPT | |
| SCHEMBL3943394 | 0.80 | MEN1 (0.40) | PARP1KDM4EMAPTRXRARXRB | |
| SCHEMBL28798205 | 0.79 | KDM4E (0.39) | PARP1KDM4EMAPT | |
| SCHEMBL5754704 | 0.75 | CYP1A2 (0.44) | PARP1MAPTRXRARXRBRXRG | |
| SCHEMBL21465443 | 0.75 | CYP1A2 (0.44) | PARP1MAPTRXRARXRBRXRG | |
| SCHEMBL6970151 | 0.75 | PARP1 (0.39) | PARP1KDM4EMAPTRXRARXRB | |
| SCHEMBL11901340 | 0.73 | PARP1 (0.44) | PARP1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007028789-A1 | QUINAZOLINE DERIVATIVES AS ANTIVIRAL AGENTS | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI SPA (IT) | 2007-03-15 | — | — | WO | disclosed |