Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | MPI | P34949 | 1/20 | 0.35 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 2/20 | 0.34 |
| ▸ | XDH | P47989 | 3/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5330428 | 0.81 | PARP1 (0.49) | PARP1MAPTKDM4E | |
| SCHEMBL3950495 | 0.81 | ALDH1A1 (0.49) | PARP1MAPTKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL31731343 | 0.79 | ALDH1A1 (0.39) | PARP1MAPTKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL3943394 | 0.77 | MEN1 (0.40) | PARP1MAPTKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL10911937 | 0.76 | ALDH1A1 (0.42) | PARP1MAPTKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL6970151 | 0.75 | PARP1 (0.39) | PARP1MAPTKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL4033116 | 0.74 | KDM4E (0.43) | PARP1MAPTKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL18575482 | 0.73 | KDM4E (0.35) | PARP1MAPTKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL31038425 | 0.73 | KDM4E (0.35) | PARP1MAPTKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL5330657 | 0.72 | HSPD1 (0.50) | MAPTKMT2ATP53ALOX15ALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007028789-A1 | QUINAZOLINE DERIVATIVES AS ANTIVIRAL AGENTS | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI SPA (IT) | 2007-03-15 | — | — | WO | disclosed |