Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.33 |
| ▸ | MEN1 | O00255 | 4/20 | 0.33 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.32 |
| ▸ | BMP1 | P13497 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.31 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7557772 | 0.88 | NPC1 (0.35) | NPC1RAB9AKMT2AMEN1MDM2 | |
| SCHEMBL3386401 | 0.87 | MDM2 (0.41) | NPC1RAB9AKMT2AMEN1MDM2 | |
| SCHEMBL8079493 | 0.84 | MEN1 (0.40) | NPC1RAB9AKMT2AMEN1MDM2 | |
| SCHEMBL4841403 | 0.84 | NPC1 (0.42) | NPC1RAB9AKMT2AMEN1HSD17B10 | |
| SCHEMBL17500350 | 0.83 | NPC1 (0.43) | NPC1RAB9AKMT2AMEN1HSD17B10 | |
| SCHEMBL2990766 | 0.82 | MEN1 (0.43) | NPC1RAB9AKMT2AMEN1HSD17B10 | |
| SCHEMBL303625 | 0.82 | NPC1 (0.42) | NPC1RAB9AKMT2AMEN1HSD17B10 | |
| Norleucine SCHEMBL7204454 | 0.82 | SLC1A5 (0.36) | NPC1RAB9AKMT2AMEN1MDM2 | |
| SCHEMBL4784032 | 0.81 | FABP5 (0.41) | RAB9AKMT2AMEN1TSHRGPR55 | |
| SCHEMBL7185186 | 0.81 | NPC1 (0.34) | NPC1RAB9AKMT2AMEN1MDM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007109609-A2 | METHOD FOR INHIBITING ANGIOGENESIS | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2007-09-27 | — | — | WO | disclosed |
| US-6936584-B1 | Mixed amylin activity compounds | AMYLIN PHARMACEUTICALS, INC. (US) | 2005-08-30 | — | — | US | disclosed |