Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8079493 | 0.90 | MEN1 (0.40) | MEN1KMT2ANPC1RAB9ATSHR | |
| SCHEMBL4841403 | 0.86 | NPC1 (0.42) | MEN1KMT2ANPC1RAB9ATSHR | |
| SCHEMBL1662186 | 0.85 | KMT2A (0.41) | MEN1KMT2ANPC1RAB9APOLB | |
| SCHEMBL17500350 | 0.85 | NPC1 (0.43) | MEN1KMT2ANPC1RAB9ATSHR | |
| SCHEMBL303625 | 0.84 | NPC1 (0.42) | MEN1KMT2ANPC1RAB9ATSHR | |
| SCHEMBL1644285 | 0.83 | MEN1 (0.35) | MEN1KMT2ANPC1RAB9ATSHR | |
| SCHEMBL5330706 | 0.82 | NPC1 (0.36) | MEN1KMT2ANPC1RAB9ATSHR | |
| SCHEMBL3433024 | 0.82 | HSD17B10 (0.39) | MEN1KMT2ANPC1RAB9ATSHR | |
| SCHEMBL7557772 | 0.82 | NPC1 (0.35) | MEN1KMT2ANPC1RAB9ATSHR | |
| SCHEMBL28069712 | 0.82 | FABP5 (0.45) | MEN1KMT2ANPC1RAB9ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8071640-B2 | Urea oligomers, their preparation process and pharmaceutical compositions containing them | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2011-12-06 | — | — | US | disclosed |
| US-20100184849-A1 | UREA OLIGOMERS, THEIR PREPARATION PROCESS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQU (FR) | 2010-07-22 | — | — | US | disclosed |
| US-7691899-B2 | Urea oligomers, the preparation method thereof and pharmaceutical composition containing same | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2010-04-06 | — | — | US | disclosed |
| US-7186739-B2 | Stabilized activated derivatives of carbamic acid, their process of preparation and their use for the preparation of ureas | IMMUPHARMA (FRANCE) SA (FR) | 2007-03-06 | — | — | US | disclosed |
| US-20050159584-A1 | Novel stabilized activated derivatives of carbamic acid, their process of preparation and their use for the preparation of ureas | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2005-07-21 | — | — | US | disclosed |
| US-20050159585-A1 | Novel stabilized activated derivatives of carbamic acid, their process of preparation and their use for the preparation of ureas | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2005-07-21 | — | — | US | disclosed |
| US-20050038105-A1 | Novel urea oligomers, the preparation method thereof and pharmaceutical composition containing same | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2005-02-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050159584-A1 | Novel stabilized activated derivatives of carbamic acid, their process of preparation and their use for the preparation of ureas | CPS1, ASNS, ACMSD | MEN1 2985/4885KMT2A 989/4885NPC1 2606/4885 |
| US-20100184849-A1 | UREA OLIGOMERS, THEIR PREPARATION PROCESS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | UACA, RAN, URB2 | MEN1 3827/4885KMT2A 4408/4885NPC1 1737/4885 |
| US-20050159585-A1 | Novel stabilized activated derivatives of carbamic acid, their process of preparation and their use for the preparation of ureas | CPS1, ASNS, ACMSD | MEN1 2985/4885KMT2A 989/4885NPC1 2606/4885 |
| US-20050038105-A1 | Novel urea oligomers, the preparation method thereof and pharmaceutical composition containing same | URB2, NOXO1, UACA | MEN1 2094/4885KMT2A 4617/4885NPC1 1327/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.