Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 6/20 | 0.54 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | HTR2C | P28335 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | DRD4 | P21917 | 1/20 | 0.47 |
| ▸ | HTR1D | P28221 | 1/20 | 0.47 |
| ▸ | HTR1B | P28222 | 1/20 | 0.47 |
| ▸ | HTR1F | P30939 | 1/20 | 0.47 |
| ▸ | HTR7 | P34969 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5332344 | 0.90 | HTR2A (0.54) | HTR6HTR2AHTR2CHTR1ADRD2 | |
| SCHEMBL5420154 | 0.83 | EGFR (0.44) | CYP19A1CYP3A4MAPTEGFRSRC | |
| Hydrochloric Acid SCHEMBL11859405 | 0.81 | HTR6 (0.53) | HTR6HTR2AHTR2CHTR1ADRD2 | |
| SCHEMBL5330477 | 0.80 | HTR2A (0.57) | HTR6HTR2AHTR2CHTR1ADRD2 | |
| SCHEMBL5378791 | 0.78 | CYP19A1 (0.38) | CYP19A1CYP3A4MAPTEGFRSRC | |
| Hydrochloric Acid SCHEMBL5330712 | 0.77 | HTR6 (0.43) | HTR6HTR2AHTR2CHTR1AHTR1D | |
| Hydrochloric Acid SCHEMBL5334181 | 0.77 | HTR6 (0.43) | HTR6HTR2AHTR2CHTR1AHTR1D | |
| Hydrochloric Acid SCHEMBL5331946 | 0.77 | HTR6 (0.55) | HTR6HTR2AHTR2CHTR1AHTR1D | |
| SCHEMBL5378787 | 0.77 | CYP19A1 (0.38) | CYP19A1EGFRSRCGAAHDAC3 | |
| SCHEMBL30485863 | 0.72 | HTR6 (0.63) | HTR6HTR2AHTR2CHTR1ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007046112-A1 | ARYLTHIOETHER TRYPTAMINE DERIVATIVES AS FUNCTIONAL 5-HT6 LIGANDS | SUVEN LIFE SCIENCES INC. (IN) | 2007-04-26 | — | — | WO | claimed |