Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 7/20 | 0.57 |
| ▸ | HTR2C | P28335 | 7/20 | 0.57 |
| ▸ | DRD2 | P14416 | 6/20 | 0.44 |
| ▸ | HTR6 | P50406 | 4/20 | 0.43 |
| ▸ | HTR1A | P08908 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MPI | P34949 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5332993 | 0.87 | MPO (0.45) | HTR2AHTR2CDRD2HTR6HTR1A | |
| Hydrochloric Acid SCHEMBL5332344 | 0.86 | HTR2A (0.54) | HTR2AHTR2CDRD2HTR6HTR1A | |
| SCHEMBL5330718 | 0.80 | HTR6 (0.54) | HTR2AHTR2CDRD2HTR6HTR1A | |
| SCHEMBL5331960 | 0.78 | CHRNB2 (0.46) | HTR2AKMT2AKDM4EALDH1A1POLB | |
| Hydrochloric Acid SCHEMBL11859405 | 0.77 | HTR6 (0.53) | HTR2AHTR2CDRD2HTR6HTR1A | |
| SCHEMBL5465765 | 0.75 | HTR2A (0.60) | HTR2AHTR2CDRD2HTR6HTR1A | |
| Hydrochloric Acid SCHEMBL5330712 | 0.74 | HTR6 (0.43) | HTR2AHTR2CHTR6HTR1AKMT2A | |
| Hydrochloric Acid SCHEMBL5334181 | 0.74 | HTR6 (0.43) | HTR2AHTR2CHTR6HTR1AMPO | |
| Hydrochloric Acid SCHEMBL5331946 | 0.74 | HTR6 (0.55) | HTR2AHTR2CHTR6HTR1AMPO | |
| SCHEMBL7645002 | 0.73 | HTR2A (1.00) | HTR2AHTR2CDRD2HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007046112-A1 | ARYLTHIOETHER TRYPTAMINE DERIVATIVES AS FUNCTIONAL 5-HT6 LIGANDS | SUVEN LIFE SCIENCES INC. (IN) | 2007-04-26 | — | — | WO | claimed |