Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | SRC | P12931 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | TDO2 | P48775 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MPI | P34949 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5330718 | 0.83 | HTR6 (0.54) | EGFRSRCPTGS2CYP19A1ALDH1A1 | |
| SCHEMBL5378791 | 0.77 | CYP19A1 (0.38) | EGFRSRCPTGS2CYP19A1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL5332344 | 0.72 | HTR2A (0.54) | ALDH1A1MAPTKMT2AKDM4EPOLB | |
| SCHEMBL5330477 | 0.71 | HTR2A (0.57) | ALDH1A1MAPTKMT2AKDM4EPOLB | |
| SCHEMBL5331960 | 0.71 | CHRNB2 (0.46) | CYP19A1ALDH1A1GFERMAPTKMT2A | |
| SCHEMBL10981391 | 0.70 | NR3C1 (0.60) | CYP19A1ALDH1A1GAAMAPTKMT2A | |
| SCHEMBL5335447 | 0.69 | DRD2 (0.50) | ALDH1A1GAAMAPTKMT2AKDM4E | |
| SCHEMBL5337329 | 0.69 | DRD2 (0.44) | PTGS2ALDH1A1MAPTKMT2AKDM4E | |
| SCHEMBL5333822 | 0.69 | MAPT (0.45) | PTGS2CYP19A1MAPTKMT2AMEN1 | |
| SCHEMBL5335619 | 0.69 | MAPT (0.45) | PTGS2MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007046112-A1 | ARYLTHIOETHER TRYPTAMINE DERIVATIVES AS FUNCTIONAL 5-HT6 LIGANDS | SUVEN LIFE SCIENCES INC. (IN) | 2007-04-26 | — | — | WO | disclosed |