SCHEMBL5330807

SCHEMBL5330807

C=Cc1ccc(-n2cc(C)c(=O)[nH]c2=O)cc1

nearest known ligand 0.42

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
PKM P14618 1/20 0.42
KMT2A Q03164 3/20 0.41
L3MBTL1 Q9Y468 1/20 0.40
MEN1 O00255 1/20 0.39
MAPK1 P28482 1/20 0.39
ALDH1A1 P00352 3/20 0.38
NPC1 O15118 1/20 0.38
MAPT P10636 1/20 0.38
RAB9A P51151 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
HPGD P15428 2/20 0.38
POLB P06746 2/20 0.34
NPSR1 Q6W5P4 1/20 0.34
HSD17B10 Q99714 1/20 0.34
LMNA P02545 1/20 0.34
ALB P02768 1/20 0.34
ADRA1A P35348 1/20 0.34
BLM P54132 1/20 0.34
TK1 P04183 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7830376 0.79 ALDH1A1 (0.47) PKMKMT2AL3MBTL1MEN1MAPK1
SCHEMBL23296150 0.79 PKM (0.45) PKMKMT2AL3MBTL1MEN1MAPK1
SCHEMBL7834516 0.78 HPGD (0.54) PKMKMT2AMAPK1ALDH1A1NPC1
SCHEMBL20577849 0.76 ATM (0.48) PKMKMT2AL3MBTL1MEN1MAPK1
SCHEMBL23345942 0.76 PKM (0.43) PKMKMT2AL3MBTL1MEN1MAPK1
SCHEMBL7833356 0.76 PKM (0.42) PKMKMT2AL3MBTL1MEN1MAPK1
SCHEMBL6333309 0.75 HPGD (0.67) MAPK1HPGD
SCHEMBL23296109 0.74 ACHE (0.46) PKMKMT2AL3MBTL1MEN1ALDH1A1
SCHEMBL5330805 0.73 MAPK1 (0.43) MAPK1HPGDTK1
SCHEMBL3346087 0.72 MAPT (0.47) PKMKMT2AL3MBTL1MEN1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007139810-A2 PHOTO-INDUCED COPOLYMER FUNCTIONALIZED SUBSTRATES UNIVERSITY OF MASSACHUSETTS (US) 2007-12-06 WO disclosed
EP-0759193-B1 VINYLBENZYL THYMINE MONOMERS AND POLYMERS AND PRODUCTS PREPARED FROM SAME POLAROID CORP (US) 1998-09-09 EP disclosed
US-5708106-A PHOTOCROSSLINKED POLAROID CORPORATION (US) 1998-01-13 US disclosed
US-5616451-A IMAGES BY EXPOSURE TO ACTINIC RADIATION; SOLVENT REMOVAL OF NON-EXPOSED AREAS POLAROID CORPORATION (US) 1997-04-01 US disclosed
EP-0759193-A1 VINYLBENZYL THYMINE MONOMERS AND POLYMERS AND PRODUCTS PREPARED FROM SAME POLAROID CORPORATION (US) 1997-02-26 EP disclosed
WO-1995031755-A1 VINYLBENZYL THYMINE MONOMERS AND POLYMERS AND PRODUCTS PREPARED FROM SAME POLAROID CORPORATION (US) 1995-11-23 WO disclosed
US-5455349-A For polymers useful in photoresists, imaging POLAROID CORPORATION (US) 1995-10-03 US disclosed
US-5395731-A Pendant quaternary ammonium and thymine or uracil groups, diffusion transfer POLAROID CORPORATION (US) 1995-03-07 US disclosed