Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 10/20 | 0.43 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.42 |
| ▸ | PGR | P06401 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5330829 | 0.85 | ABCB1 (0.39) | PTGS2PTGS1ALDH1A1LMNAHTT | |
| SCHEMBL5330835 | 0.82 | PTGS2 (0.48) | PTGS2MAPTPTGS1KDM4ELMNA | |
| SCHEMBL5311718 | 0.76 | PTGS2 (0.69) | PTGS2PTGS1 | |
| SCHEMBL321448 | 0.73 | PTGS2 (0.52) | PTGS2NR3C1PGRMAPTTHRB | |
| Hydrochloric Acid SCHEMBL7991387 | 0.72 | PTGS2 (0.50) | PTGS2NR3C1PGRMAPTTHRB | |
| SCHEMBL12328072 | 0.67 | PTGS2 (0.73) | PTGS2MAPTPTGS1ALDH1A1KDM4E | |
| SCHEMBL29438438 | 0.65 | CA12 (0.52) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL1313610 | 0.65 | CA12 (0.52) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL3633054 | 0.64 | CA12 (0.61) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL29551674 | 0.64 | CA12 (0.61) | CA12CA1CA2CA9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0799823-B1 | 1,2-Diphenylpyrrole derivatives, their preparation and their therapeutic uses | DAIICHI SANKYO CO LTD (JP) | 2007-10-31 | — | — | EP | disclosed |