Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 8/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5330835 | 0.85 | PTGS2 (0.48) | ABCB1PTGS2PTGS1KMT2AMEN1 | |
| SCHEMBL5330822 | 0.85 | PTGS2 (0.43) | PTGS2PTGS1ALDH1A1LMNAHTT | |
| SCHEMBL5311718 | 0.71 | PTGS2 (0.69) | PTGS2PTGS1 | |
| SCHEMBL4064478 | 0.65 | MAPK14 (0.47) | ABCB1NPSR1RXFP1PTGS1ALDH1A1 | |
| SCHEMBL13702959 | 0.65 | MAPK14 (0.47) | ABCB1NPSR1RXFP1PTGS1ALDH1A1 | |
| SCHEMBL17662179 | 0.65 | PTGS2 (0.50) | PTGS2PTGS1ALDH1A1NPC1SLC6A4 | |
| SCHEMBL17662141 | 0.65 | F2 (0.48) | ALDH1A1KMT2AMEN1NPC1RAB9A | |
| SCHEMBL9039798 | 0.65 | ALDH1A1 (0.41) | PTGS2NPSR1ALDH1A1KMT2AMEN1 | |
| SCHEMBL8036362 | 0.64 | LMNA (0.50) | ABCB1PTGS2ALDH1A1KMT2AMEN1 | |
| SCHEMBL2593840 | 0.63 | IDO1 (0.49) | NPSR1RXFP1ALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0799823-B1 | 1,2-Diphenylpyrrole derivatives, their preparation and their therapeutic uses | DAIICHI SANKYO CO LTD (JP) | 2007-10-31 | — | — | EP | disclosed |