Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 10/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5330829 | 0.85 | ABCB1 (0.39) | PTGS2KMT2APTGS1MEN1ACHE | |
| SCHEMBL5330822 | 0.82 | PTGS2 (0.43) | PTGS2PTGS1KDM4EMAPTLMNA | |
| SCHEMBL5311718 | 0.82 | PTGS2 (0.69) | PTGS2PTGS1 | |
| SCHEMBL13231751 | 0.73 | PTGS2 (0.58) | PTGS2KMT2APTGS1MEN1KDM4E | |
| SCHEMBL12328072 | 0.72 | PTGS2 (0.73) | PTGS2KMT2APTGS1MEN1KDM4E | |
| SCHEMBL9039798 | 0.69 | ALDH1A1 (0.41) | PTGS2KMT2AMEN1KDM4EMAPT | |
| SCHEMBL20804472 | 0.69 | ACHE (0.81) | KMT2APTGS1MEN1ACHENPC1 | |
| SCHEMBL422511 | 0.69 | ACHE (0.81) | KMT2APTGS1MEN1ACHENPC1 | |
| SCHEMBL12980347 | 0.68 | PTGS2 (0.44) | PTGS2KMT2APTGS1MEN1ACHE | |
| SCHEMBL3035449 | 0.66 | PTGS2 (0.75) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0799823-B1 | 1,2-Diphenylpyrrole derivatives, their preparation and their therapeutic uses | DAIICHI SANKYO CO LTD (JP) | 2007-10-31 | — | — | EP | disclosed |