Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.43 |
| ▸ | MEN1 | O00255 | 6/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30211090 | 0.86 | KMT2A (0.41) | KMT2AMEN1MAPTGAAKDM4E | |
| SCHEMBL27682291 | 0.72 | KMT2A (0.44) | KMT2AMEN1MAPTGAAKDM4E | |
| SCHEMBL8654683 | 0.69 | KMT2A (0.41) | KMT2AMEN1MAPTGAAKDM4E | |
| SCHEMBL7559328 | 0.68 | ADRB2 (0.55) | KMT2AMEN1MAPTKDM4EHSP90AA1 | |
| SCHEMBL8523571 | 0.68 | KMT2A (0.43) | KMT2AMEN1MAPTGAAKDM4E | |
| SCHEMBL9306101 | 0.67 | KMT2A (0.48) | KMT2AMEN1MAPTGAAKDM4E | |
| SCHEMBL31020734 | 0.67 | KMT2A (0.51) | KMT2AMEN1MAPTGAAKDM4E | |
| Hydrochloric Acid SCHEMBL7554207 | 0.67 | MAPT (0.55) | KMT2AMEN1MAPTKDM4EHSP90AA1 | |
| SCHEMBL29280158 | 0.66 | ALDH1A1 (0.61) | KMT2AMEN1MAPTKDM4EHSP90AA1 | |
| SCHEMBL27553570 | 0.66 | KMT2A (0.41) | KMT2AMEN1MAPTGAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007047579-A2 | A NOVEL THERAPEUTIC TARGET FOR PROTOZOAL DISEASES | VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (US) | 2007-04-26 | — | — | WO | claimed |
| CN-1344135-A | Organ arrest, protection and preservation | UNIV JAMES COOK (AU) | 2002-04-10 | — | — | CN | disclosed |