Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 14/20 | 0.45 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5330681 | 0.84 | HTR6 (0.49) | HTR6 | |
| SCHEMBL5330679 | 0.79 | HTR6 (0.49) | HTR6CYP3A4CYP2D6 | |
| SCHEMBL5327034 | 0.72 | HTR6 (0.49) | HTR6 | |
| SCHEMBL5329599 | 0.72 | HTR6 (0.53) | HTR6 | |
| SCHEMBL5333397 | 0.71 | HTR6 (0.53) | HTR6 | |
| SCHEMBL18581022 | 0.71 | HTR6 (0.47) | HTR6CYP3A4CYP2D6 | |
| SCHEMBL16619154 | 0.69 | KDM4E (0.44) | HTR6RORCHTT | |
| SCHEMBL12096636 | 0.69 | HTR6 (0.46) | HTR6CYP3A4CYP2D6HTT | |
| SCHEMBL28857521 | 0.68 | RORC (0.57) | HTR6RORCHTT | |
| SCHEMBL16619008 | 0.67 | PLK1 (0.55) | HTR6DDR1RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007020653-A1 | THIOETHER DERIVATIVES AS FUNCTIONAL 5-HT6 LIGANDS | SUVEN LIFE SCIENCES LIMITED (IN) | 2007-02-22 | — | — | WO | claimed |