Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.57 |
| ▸ | LMNA | P02545 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | TDP2 | O95551 | 1/20 | 0.53 |
| ▸ | NSD2 | O96028 | 1/20 | 0.53 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.53 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | FEN1 | P39748 | 1/20 | 0.48 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4754692 | 0.85 | ALDH1A1 (0.65) | KDM4EALDH1A1LMNAMAPTGAA | |
| SCHEMBL1522936 | 0.84 | KDM4E (0.81) | KDM4EALDH1A1LMNAMAPTGAA | |
| SCHEMBL5529505 | 0.84 | ALDH1A1 (0.81) | KDM4EALDH1A1LMNAMAPTGAA | |
| SCHEMBL15966795 | 0.84 | ALDH1A1 (0.67) | KDM4EALDH1A1LMNAMAPTGAA | |
| SCHEMBL11377362 | 0.83 | ALDH1A1 (0.67) | KDM4EALDH1A1LMNAMAPTRECQL | |
| SCHEMBL5124064 | 0.83 | ALDH1A1 (0.63) | KDM4EALDH1A1LMNAMAPTGAA | |
| SCHEMBL14607234 | 0.82 | ALDH1A1 (0.62) | KDM4EALDH1A1LMNAMAPTGAA | |
| SCHEMBL8250095 | 0.81 | EGLN1 (0.70) | KDM4EALDH1A1LMNAMAPTTSHR | |
| SCHEMBL5334611 | 0.81 | KDM4E (0.59) | KDM4EALDH1A1LMNAMAPTGAA | |
| SCHEMBL11393959 | 0.81 | LMNA (0.67) | KDM4EALDH1A1LMNATSHRRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007038571-A2 | PROLYL HYDROXYLASE ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2007-04-05 | — | — | WO | disclosed |