Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | HTR1D | P28221 | 1/20 | 0.32 |
| ▸ | HTR1B | P28222 | 1/20 | 0.32 |
| ▸ | IDH1 | O75874 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.30 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.30 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4521525 | 1.00 | LTA4H (0.35) | LTA4HNPC1RAB9AMEN1KMT2A | |
| SCHEMBL4513365 | 0.92 | NPC1 (0.34) | LTA4HNPC1RAB9AMEN1KMT2A | |
| SCHEMBL4516293 | 0.90 | ALDH1A1 (0.33) | LTA4HNPC1RAB9AMEN1KMT2A | |
| SCHEMBL4515171 | 0.90 | LTA4H (0.36) | LTA4HNPC1RAB9AMEN1KMT2A | |
| SCHEMBL4238871 | 0.84 | LTA4H (0.37) | LTA4HNPC1RAB9AMEN1KMT2A | |
| SCHEMBL4522278 | 0.84 | CTSL (0.35) | HTR1DHTR1BIDH1 | |
| SCHEMBL4522276 | 0.84 | CTSL (0.35) | HTR1DHTR1BIDH1 | |
| SCHEMBL13757308 | 0.83 | PPARG (0.37) | NPC1HTR1DHTR1BIDH1 | |
| SCHEMBL4235041 | 0.83 | NPC1 (0.33) | LTA4HNPC1RAB9AMEN1KMT2A | |
| SCHEMBL4501784 | 0.82 | ALDH1A1 (0.33) | LTA4HNPC1RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007029062-A2 | NOVEL PYRIDINE DERIVATIVES | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2007-03-15 | — | — | WO | claimed |
| WO-2007029062-A2 | NOVEL PYRIDINE DERIVATIVES | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2007-03-15 | — | — | WO | disclosed |