Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | GMNN | O75496 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TLR2 | O60603 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | PRKCA | P17252 | 3/20 | 0.31 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.31 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.31 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.31 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5328136 | 0.91 | METAP2 (0.33) | — | |
| SCHEMBL5325063 | 0.87 | MAPT (0.33) | MAPTGMNNTP53POLBTHRB | |
| SCHEMBL5328473 | 0.84 | OR51E2 (0.30) | — | |
| SCHEMBL4951686 | 0.83 | MAPT (0.35) | MAPTGMNNTP53POLBTHRB | |
| SCHEMBL4952141 | 0.83 | GMNN (0.35) | MAPTGMNNTP53POLBTHRB | |
| SCHEMBL4954139 | 0.81 | MAPT (0.36) | MAPTGMNNTP53POLBTHRB | |
| SCHEMBL4951744 | 0.81 | CES2 (0.38) | MAPTGMNNTP53POLBTHRB | |
| SCHEMBL4951868 | 0.80 | MAPT (0.37) | MAPTGMNNTP53POLBTHRB | |
| SCHEMBL5329279 | 0.79 | RNPEP (0.31) | — | |
| SCHEMBL4954119 | 0.78 | LMNA (0.39) | MAPTGMNNTP53POLBTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007147155-A1 | POLYOL ESTER COMPOUNDS | NOVUS INTERNATIONAL INC. (US) | 2007-12-21 | — | — | WO | disclosed |