Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 14/20 | 0.62 |
| ▸ | THRA | P10827 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5328482 | 0.86 | ALDH1A1 (0.52) | THRBKMT2AALDH1A1TSHR | |
| SCHEMBL5326045 | 0.84 | THRB (0.44) | THRBTHRA | |
| SCHEMBL5330145 | 0.84 | THRB (0.47) | THRBTHRA | |
| SCHEMBL5327964 | 0.83 | THRB (0.47) | THRBTHRA | |
| SCHEMBL5324972 | 0.83 | THRB (0.66) | THRBTHRAALDH1A1L3MBTL1 | |
| SCHEMBL5325777 | 0.82 | THRB (0.43) | THRBTHRA | |
| SCHEMBL6660358 | 0.82 | THRB (0.61) | THRBTHRAKMT2AALDH1A1ALOX15 | |
| SCHEMBL5328330 | 0.82 | THRB (0.43) | THRBTHRAKMT2AMEN1TSHR | |
| SCHEMBL5332095 | 0.81 | THRB (0.63) | THRBTHRAALDH1A1 | |
| SCHEMBL5327217 | 0.79 | THRB (0.53) | THRBTHRAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007132475-A1 | SELECTIVE TR-BETA 1 AGONIST | CADILA HEALTHCARE LIMITED (IN) | 2007-11-22 | — | — | WO | disclosed |