Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | THRB | P10828 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5331464 | 0.86 | THRB (0.62) | ALDH1A1TSHRKMT2ATHRB | |
| SCHEMBL5326299 | 0.85 | L3MBTL1 (0.49) | ALDH1A1KDM4EPOLBHPGDRAB9A | |
| SCHEMBL5323684 | 0.85 | TSHR (0.40) | ALDH1A1KDM4EPOLBHPGDRAB9A | |
| SCHEMBL5326354 | 0.84 | THRB (0.51) | ALDH1A1KMT2ATHRBPKM | |
| SCHEMBL5331463 | 0.84 | TSHR (0.38) | ALDH1A1KDM4EPOLBHPGDRAB9A | |
| SCHEMBL5327154 | 0.83 | TSHR (0.43) | ALDH1A1KDM4EPOLBRAB9ATSHR | |
| SCHEMBL5329550 | 0.82 | THRB (0.39) | ALDH1A1KDM4EPOLBHPGDRAB9A | |
| SCHEMBL5330286 | 0.81 | THRB (0.49) | ALDH1A1KDM4EPOLBHPGDKMT2A | |
| SCHEMBL5324510 | 0.80 | THRB (0.38) | ALDH1A1RAB9ATHRBNPBWR1LMNA | |
| SCHEMBL5323874 | 0.79 | RORC (0.55) | THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007132475-A1 | SELECTIVE TR-BETA 1 AGONIST | CADILA HEALTHCARE LIMITED (IN) | 2007-11-22 | — | — | WO | disclosed |