Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 12/20 | 0.54 |
| ▸ | HTR1B | P28222 | 12/20 | 0.54 |
| ▸ | HTR1A | P08908 | 2/20 | 0.54 |
| ▸ | HTR1F | P30939 | 2/20 | 0.54 |
| ▸ | CCR2 | P41597 | 6/20 | 0.47 |
| ▸ | BTK | Q06187 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5322832 | 0.86 | HTR1D (0.54) | HTR1DHTR1BHTR1AHTR1FCCR2 | |
| SCHEMBL27481407 | 0.76 | HTR1D (0.68) | HTR1DHTR1BHTR1AHTR1FBTK | |
| SCHEMBL2935082 | 0.74 | HTR1D (0.61) | HTR1DHTR1BHTR1AHTR1FBTK | |
| SCHEMBL8067557 | 0.74 | HTR1D (0.53) | HTR1DHTR1BHTR1AHTR1FBTK | |
| SCHEMBL4676594 | 0.74 | SLC6A4 (0.53) | — | |
| SCHEMBL5456752 | 0.73 | HTR1D (0.62) | HTR1DHTR1BHTR1AHTR1FCCR2 | |
| SCHEMBL5328392 | 0.72 | OPRM1 (0.46) | HTR1DHTR1BCCR2BTK | |
| SCHEMBL7487827 | 0.72 | HTR1D (1.00) | HTR1DHTR1BHTR1AHTR1F | |
| SCHEMBL4671108 | 0.72 | JAK2 (0.45) | HTR1DHTR1BBTK | |
| SCHEMBL8096479 | 0.71 | HSD11B1 (0.55) | HTR1DHTR1BHTR1ABTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007130712-A1 | SUBSTITUTED DIPIPERIDINE AS CCR2 ANTAGONISTS FOR THE TREATMENT OF INFLAMMATORY DISEASES | JANSSEN PHARMACEUTICA, NV (BE) | 2007-11-15 | — | — | WO | disclosed |