Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5328035 | 0.91 | THRB (0.42) | KMT2AMEN1TDP1HSP90AA1HSD17B10 | |
| SCHEMBL5333097 | 0.90 | THRB (0.39) | KMT2AMEN1HSD17B10KDM4EALDH1A1 | |
| SCHEMBL5326974 | 0.80 | THRB (0.49) | HSD17B10KDM4EALDH1A1HPGDTSHR | |
| SCHEMBL5328999 | 0.74 | THRB (0.52) | KMT2AMEN1KDM4EALDH1A1HPGD | |
| SCHEMBL5330302 | 0.72 | MEN1 (0.48) | KMT2AMEN1 | |
| SCHEMBL6219048 | 0.71 | THRB (0.60) | — | |
| SCHEMBL5325834 | 0.70 | PDE4A (0.37) | KMT2AMEN1KDM4EALDH1A1POLB | |
| SCHEMBL6221593 | 0.69 | HSP90AA1 (0.42) | KMT2AMEN1TDP1HSP90AA1ALDH1A1 | |
| SCHEMBL4251171 | 0.69 | TAS1R3 (0.40) | KMT2AMEN1TDP1HSP90AA1HSD17B10 | |
| SCHEMBL3219307 | 0.68 | KMT2A (0.42) | KMT2AMEN1TDP1HSP90AA1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007132475-A1 | SELECTIVE TR-BETA 1 AGONIST | CADILA HEALTHCARE LIMITED (IN) | 2007-11-22 | — | — | WO | claimed |