Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.41 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.41 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | SRC | P12931 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5314760 | 0.86 | MEN1 (0.57) | MEN1KMT2ACSNK2A1NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL5369271 | 0.85 | MEN1 (0.56) | MEN1KMT2ACSNK2A1NPC1SRC | |
| SCHEMBL5331600 | 0.78 | EPAS1 (0.52) | MEN1KMT2ACSNK2A1CSNK2A2CSNK2B | |
| SCHEMBL5343088 | 0.78 | RAB9A (0.66) | MEN1KMT2ACSNK2A1CSNK2A2CSNK2B | |
| SCHEMBL5334384 | 0.75 | MAPT (0.42) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL5335403 | 0.74 | NPC1 (0.46) | MEN1KMT2ACSNK2A1CSNK2A2CSNK2B | |
| SCHEMBL5458331 | 0.73 | MEN1 (0.47) | MEN1KMT2ACSNK2A1NPC1SRC | |
| SCHEMBL5334156 | 0.73 | MEN1 (0.46) | MEN1KMT2ACSNK2A1NPC1RAB9A | |
| SCHEMBL5311682 | 0.71 | CSNK2A2 (0.41) | MEN1KMT2ACSNK2A1CSNK2A2CSNK2B | |
| Hydrochloric Acid SCHEMBL5332537 | 0.71 | NPC1 (0.43) | MEN1KMT2ACSNK2A1CSNK2A2CSNK2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007056215-A9 | N-ARYL-THIENOPYRIMIDIN-4-AMINES AND THE USE THEREOF | CYTOVIA INC (US) | 2007-09-13 | — | — | WO | claimed |
| WO-2007056215-A2 | N-ARYL-THIENOPYRIMIDIN-4-AMINES AND THE USE THEREOF | CYTOVIA, INC. (US) | 2007-05-18 | — | — | WO | claimed |