Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCAT1 | P54687 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | PTPN22 | Q9Y2R2 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP3 | P08254 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | MMP14 | P50281 | 1/20 | 0.40 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.40 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.40 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4926908 | 0.75 | ALDH1A1 (0.51) | BCAT1ALDH1A1HPGDPTPN22KDM4E | |
| SCHEMBL4925998 | 0.75 | LIMK1 (0.53) | BCAT1ALDH1A1HPGDPTPN22KMT2A | |
| SCHEMBL4924372 | 0.70 | AKR1B1 (0.53) | BCAT1ALDH1A1KDM4EKMT2ANPC1 | |
| SCHEMBL4916668 | 0.70 | TP53 (0.72) | BCAT1ALDH1A1HPGDKMT2ANPC1 | |
| SCHEMBL657436 | 0.70 | NPC1 (0.69) | BCAT1ALDH1A1HPGDKDM4EKMT2A | |
| SCHEMBL30629235 | 0.70 | NPC1 (0.69) | BCAT1ALDH1A1HPGDKDM4EKMT2A | |
| SCHEMBL29526778 | 0.70 | PIM1 (0.64) | BCAT1ALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL705754 | 0.70 | PIM1 (0.64) | BCAT1ALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL7588083 | 0.69 | BCAT1 (0.45) | BCAT1ALDH1A1HPGDPTPN22KDM4E | |
| SCHEMBL14346175 | 0.68 | PPARA (0.43) | ALDH1A1HPGDKDM4EKMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007138112-A2 | COMPOUNDS THAT INTERACT WITH ION CHANNELS, IN PARTICULAR WITH ION CHANNELS FROM THE KV FAMILY | DEVGEN N.V. (BE) | 2007-12-06 | — | — | WO | claimed |
| WO-2007138112-A2 | COMPOUNDS THAT INTERACT WITH ION CHANNELS, IN PARTICULAR WITH ION CHANNELS FROM THE KV FAMILY | DEVGEN N.V. (BE) | 2007-12-06 | — | — | WO | disclosed |