Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.44 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.37 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5331061 | 0.86 | TDP1 (0.40) | ADRB2ADRB1ADRB3ALOX5CHRNB2 | |
| SCHEMBL5331040 | 0.84 | HPGD (0.40) | ADRB2ADRB1ADRB3ALOX5HPGD | |
| SCHEMBL5331767 | 0.83 | FAAH (0.40) | HPGDOPRM1OPRD1OPRK1FAAH | |
| SCHEMBL5329666 | 0.82 | EPHX2 (0.40) | ADRB2ADRB1ADRB3ALOX5CASP1 | |
| SCHEMBL5331118 | 0.80 | ADRB2 (0.40) | ADRB2ADRB1ADRB3CASP1SMN1; SMN2 | |
| SCHEMBL5324750 | 0.77 | TDP1 (0.43) | ADRB2ADRB1ADRB3ALOX5CHRNB2 | |
| SCHEMBL5330532 | 0.77 | SMN1; SMN2 (0.41) | ADRB2ADRB1ADRB3ALOX5HPGD | |
| SCHEMBL5331601 | 0.74 | FAAH (0.39) | ALOX5HPGDCHRNB2CHRNB4CHRNA3 | |
| SCHEMBL5463947 | 0.73 | HPGD (0.38) | ADRB2ADRB1ADRB3ALOX5HPGD | |
| SCHEMBL19024934 | 0.71 | ADRB2 (0.57) | ADRB2ADRB1ADRB3ALOX5HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007146086-A1 | CREATINE PRODRUGS, COMPOSITIONS AND USES THEREOF | XENOPORT, INC. (US) | 2007-12-21 | — | — | WO | disclosed |