Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 6/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | ACE | P12821 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5330532 | 0.92 | SMN1; SMN2 (0.41) | HPGDFAAHSMN1; SMN2MGLLADRB2 | |
| SCHEMBL5331767 | 0.90 | FAAH (0.40) | HPGDFAAHOPRM1OPRD1OPRK1 | |
| SCHEMBL5331601 | 0.89 | FAAH (0.39) | HPGDFAAHPPARGSMN1; SMN2MGLL | |
| SCHEMBL5331768 | 0.84 | ADRB2 (0.44) | HPGDFAAHOPRM1OPRD1OPRK1 | |
| SCHEMBL5329549 | 0.82 | TDP1 (0.39) | FAAHACECHRNB2CHRNB4CHRNA3 | |
| SCHEMBL5331057 | 0.76 | FAAH (0.38) | FAAHSMN1; SMN2 | |
| SCHEMBL5422914 | 0.76 | ACE (0.41) | FAAHACEPPARGPPARA | |
| SCHEMBL5330165 | 0.74 | FOLH1 (0.39) | FAAH | |
| SCHEMBL5324557 | 0.74 | TSHR (0.46) | SMN1; SMN2ADRB2ADRB1ADRB3LMNA | |
| SCHEMBL5324777 | 0.73 | FOLH1 (0.36) | HPGDFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007146086-A1 | CREATINE PRODRUGS, COMPOSITIONS AND USES THEREOF | XENOPORT, INC. (US) | 2007-12-21 | — | — | WO | disclosed |