SCHEMBL5331793

SCHEMBL5331793

CCN(c1ccccc1)c1nnc(-c2c(OS(=O)(=O)C(F)(F)F)ccc3ccccc23)c2ccccc12

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EGFR P00533 2/20 0.33
CSF1R P07333 2/20 0.33
APAF1 O14727 1/20 0.33
CASP3 P42574 1/20 0.33
CASP6 P55212 1/20 0.33
SENP8 Q96LD8 1/20 0.33
SENP7 Q9BQF6 1/20 0.33
SENP6 Q9GZR1 1/20 0.33
ADORA2A P29274 1/20 0.32
ADORA1 P30542 1/20 0.32
NR3C2 P08235 1/20 0.31
MAPT P10636 2/20 0.30
ALDH1A1 P00352 1/20 0.30
SMN1; SMN2 Q16637 2/20 0.30
NPC1 O15118 1/20 0.30
RAB9A P51151 1/20 0.30
LMNA P02545 1/20 0.30
HTR1A P08908 1/20 0.30
HTR1D P28221 1/20 0.30
HTR1B P28222 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13138600 0.80 ADORA2A (0.36) ADORA2AADORA1MAPTALDH1A1SMN1; SMN2
SCHEMBL3076140 0.78 ADORA2A (0.41) ADORA2AADORA1MAPTSMN1; SMN2NPC1
SCHEMBL635407 0.74 MAPT (0.49) ADORA2AADORA1MAPTALDH1A1SMN1; SMN2
SCHEMBL29560409 0.74 MAPT (0.49) ADORA2AADORA1MAPTALDH1A1SMN1; SMN2
SCHEMBL5325178 0.74 MAPT (0.34) ADORA2AADORA1MAPT
SCHEMBL5325182 0.74 CNR1 (0.40) ADORA2AADORA1MAPTALDH1A1SMN1; SMN2
SCHEMBL5331797 0.73 NPC1 (0.45) EGFRALDH1A1NPC1RAB9ALMNA
SCHEMBL12792077 0.72 CCNE2 (0.41) EGFRMAPTALDH1A1
SCHEMBL12792113 0.72 CCNE2 (0.41) EGFRMAPTALDH1A1
SCHEMBL3072846 0.72 GAA (0.33) ALDH1A1SLC2A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1773853-A1 MONOPHOSPHINE COMPOUNDS, TRANSITION METAL COMPLEXES THEREOF AND PRODUCTION OF OPTICALLY ACTIVE COMPOUNDS USING THE COMPLEXES AS ASYMMETRIC CATALYSTS Sumitomo Chemical Company, Limited (JP) 2007-04-18 EP disclosed
WO-2005121157-A1 MONOPHOSPHINE COMPOUNDS, TRANSITION METAL COMPLEXES THEREOF AND PRODUCTION OF OPTICALLY ACTIVE COMPOUNDS USING THE COMPLEXES AS ASYMMETRIC CATALYSTS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2005-12-22 WO disclosed