Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | APP | P05067 | 7/20 | 0.38 |
| ▸ | ACHE | P22303 | 6/20 | 0.38 |
| ▸ | BCHE | P06276 | 3/20 | 0.38 |
| ▸ | PDE5A | O76074 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5325182 | 0.81 | CNR1 (0.40) | NPC1RAB9AKMT2ALMNAHTT | |
| SCHEMBL12792113 | 0.79 | CCNE2 (0.41) | KMT2AEGFRHTTHPGDALDH1A1 | |
| SCHEMBL12792077 | 0.79 | CCNE2 (0.41) | KMT2AEGFRHTTHPGDALDH1A1 | |
| SCHEMBL3076140 | 0.79 | ADORA2A (0.41) | NPC1RAB9ALMNAMAPK1 | |
| SCHEMBL13138600 | 0.79 | ADORA2A (0.36) | NPC1RAB9AKMT2AALDH1A1 | |
| SCHEMBL3072846 | 0.77 | GAA (0.33) | HTTHPGDNPSR1ALDH1A1 | |
| SCHEMBL29560409 | 0.75 | MAPT (0.49) | NPC1RAB9AKMT2AALDH1A1 | |
| SCHEMBL635407 | 0.75 | MAPT (0.49) | NPC1RAB9AKMT2AALDH1A1 | |
| SCHEMBL5331793 | 0.73 | EGFR (0.33) | NPC1RAB9AEGFRLMNAMAPK1 | |
| SCHEMBL5325178 | 0.73 | MAPT (0.34) | HTTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1773853-A1 | MONOPHOSPHINE COMPOUNDS, TRANSITION METAL COMPLEXES THEREOF AND PRODUCTION OF OPTICALLY ACTIVE COMPOUNDS USING THE COMPLEXES AS ASYMMETRIC CATALYSTS | Sumitomo Chemical Company, Limited (JP) | 2007-04-18 | — | — | EP | disclosed |
| WO-2005121157-A1 | MONOPHOSPHINE COMPOUNDS, TRANSITION METAL COMPLEXES THEREOF AND PRODUCTION OF OPTICALLY ACTIVE COMPOUNDS USING THE COMPLEXES AS ASYMMETRIC CATALYSTS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2005-12-22 | — | — | WO | disclosed |