SCHEMBL5332134

SCHEMBL5332134

CSCCC(NC(=O)C(CO)C(=O)O)C(=O)O

nearest known ligand 0.57

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.50
LTA4H P09960 1/20 0.47
ALDH1A1 P00352 2/20 0.47
NPSR1 Q6W5P4 1/20 0.47
FOLH1 Q04609 1/20 0.45
CA2 P00918 2/20 0.45
MAPK1 P28482 2/20 0.45
CA1 P00915 1/20 0.45
FNTA P49354 2/20 0.44
FNTB P49356 2/20 0.44
PGGT1B P53609 1/20 0.44
USP2 O75604 1/20 0.44
TP53 P04637 1/20 0.44
ALOX15 P16050 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6010238 0.85 LMNA (0.49) LMNALTA4HALDH1A1NPSR1FOLH1
SCHEMBL5332357 0.84 MME (0.46) LMNAFOLH1
SCHEMBL2549621 0.83 LMNA (0.51) LMNACA2CA1FNTAFNTB
SCHEMBL14500882 0.83 LMNA (0.51) LMNACA2CA1FNTAFNTB
SCHEMBL5330523 0.83 MME (0.41) LMNA
SCHEMBL29204872 0.82 LMNA (0.53) LMNALTA4HALDH1A1NPSR1FOLH1
SCHEMBL5325870 0.82 MME (0.40) LMNALTA4H
SCHEMBL11434654 0.81 FNTA (0.49) LTA4HFNTAFNTBPGGT1B
SCHEMBL4957057 0.81 LMNA (0.51) LMNALTA4HALDH1A1NPSR1FOLH1
SCHEMBL4572626 0.81 LMNA (0.51) LMNALTA4HALDH1A1NPSR1FOLH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007147155-A1 POLYOL ESTER COMPOUNDS NOVUS INTERNATIONAL INC. (US) 2007-12-21 WO disclosed
US-20070292485-A1 POLYOL ESTER COMPOUNDS NOVUS INTERNATIONAL INC. (US) 2007-12-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070292485-A1 POLYOL ESTER COMPOUNDS PNLIP, ELOVL1, ELOVL5 LMNA 1572/4885LTA4H 685/4885ALDH1A1 679/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.