Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | ACLY | P53396 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | FASN | P49327 | 1/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22003827 | 0.85 | HDAC6 (0.55) | KMT2AACLY | |
| SCHEMBL27834506 | 0.82 | KMT2A (0.50) | KMT2AACLYKDM4ECYP19A1HPGD | |
| SCHEMBL22887216 | 0.82 | KMT2A (0.66) | KMT2AKDM4ECYP19A1HPGDALDH1A1 | |
| SCHEMBL22004340 | 0.81 | L3MBTL1 (0.51) | KMT2AACLYHPGDTP53ALDH1A1 | |
| SCHEMBL9085554 | 0.81 | KDM4E (0.49) | KMT2AACLYKDM4EHPGDTP53 | |
| SCHEMBL22021802 | 0.81 | ALDH1A1 (0.52) | KMT2AACLYKDM4EHPGDTP53 | |
| SCHEMBL22004341 | 0.81 | ACLY (0.46) | KMT2AACLYKDM4EHPGDTP53 | |
| SCHEMBL12094387 | 0.80 | HAO1 (0.55) | KMT2AACLYKDM4EHPGDTP53 | |
| SCHEMBL20473138 | 0.79 | KMT2A (0.66) | KMT2AKDM4ECYP19A1HPGDALDH1A1 | |
| SCHEMBL10746612 | 0.78 | HPGD (0.66) | KMT2AACLYKDM4EHPGDTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1807403-A2 | TETRACYCLIC INDOLE DERIVATIVES AS ANTIVIRAL AGENTS | Istituto di Richerche di Biologia Molecolare P. Angeletti S.p.A. (IT) | 2007-07-18 | — | — | EP | disclosed |
| WO-2006046030-A2 | TETRACYCLIC INDOLE DERIVATIVES AS ANTIVIRAL AGENTS | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P ANGELETTI SPA (IT) | 2006-05-04 | — | — | WO | disclosed |