Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLK1 | P49759 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | EPAS1 | Q99814 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 5/20 | 0.33 |
| ▸ | KDM1A | O60341 | 2/20 | 0.33 |
| ▸ | LCK | P06239 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 2/20 | 0.33 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.31 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.31 |
| ▸ | IGF1R | P08069 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5371558 | 0.81 | CLK1 (0.47) | CLK1RAB9AEPAS1MEN1NPC1 | |
| SCHEMBL5312141 | 0.71 | FBP1 (0.35) | CLK1EPAS1MEN1KMT2AEGFR | |
| SCHEMBL5335568 | 0.70 | EGFR (0.46) | CLK1NPC1EGFRLCKMAPT | |
| SCHEMBL5468583 | 0.66 | RAB9A (0.67) | RAB9AMEN1NPC1KMT2AEGFR | |
| SCHEMBL5314126 | 0.65 | CSNK2A1 (0.39) | EPAS1EGFRKDM1AKDRPDGFRB | |
| Hydrochloric Acid SCHEMBL5332537 | 0.65 | NPC1 (0.43) | CLK1RAB9AEPAS1MEN1NPC1 | |
| SCHEMBL5467523 | 0.65 | RAB9A (0.76) | CLK1RAB9AMEN1NPC1KMT2A | |
| SCHEMBL5312123 | 0.64 | EGFR (0.49) | CLK1RAB9AMEN1NPC1KMT2A | |
| Hydrochloric Acid SCHEMBL5334353 | 0.63 | EGFR (0.48) | CLK1RAB9AMEN1NPC1KMT2A | |
| SCHEMBL5330964 | 0.61 | CSNK2A1 (0.35) | CLK1RAB9AEPAS1MEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007056215-A2 | N-ARYL-THIENOPYRIMIDIN-4-AMINES AND THE USE THEREOF | CYTOVIA, INC. (US) | 2007-05-18 | — | — | WO | disclosed |