Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.67 |
| ▸ | NPC1 | O15118 | 3/20 | 0.67 |
| ▸ | MEN1 | O00255 | 5/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.66 |
| ▸ | PIP4K2A | P48426 | 3/20 | 0.51 |
| ▸ | PIP4K2B | P78356 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | EGFR | P00533 | 2/20 | 0.49 |
| ▸ | FADS1 | O60427 | 1/20 | 0.49 |
| ▸ | PIP4K2C | Q8TBX8 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | TNF | P01375 | 1/20 | 0.46 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5315096 | 0.89 | RAB9A (0.79) | RAB9ANPC1MEN1KMT2APIP4K2A | |
| SCHEMBL5312123 | 0.81 | EGFR (0.49) | RAB9ANPC1MEN1KMT2AMAPT | |
| Hydrochloric Acid SCHEMBL5334353 | 0.81 | EGFR (0.48) | RAB9ANPC1MEN1KMT2AMAPT | |
| Hydrochloric Acid SCHEMBL5332537 | 0.81 | NPC1 (0.43) | RAB9ANPC1MEN1KMT2AMAPT | |
| SCHEMBL5371558 | 0.74 | CLK1 (0.47) | RAB9ANPC1MEN1KMT2APIP4K2A | |
| SCHEMBL5466877 | 0.73 | MEN1 (0.84) | RAB9ANPC1MEN1KMT2AKDM4E | |
| Hydrochloric Acid SCHEMBL5369266 | 0.72 | MEN1 (0.82) | RAB9ANPC1MEN1KMT2AKDM4E | |
| SCHEMBL5330964 | 0.72 | CSNK2A1 (0.35) | RAB9ANPC1MEN1KMT2AKDM4E | |
| SCHEMBL5314126 | 0.71 | CSNK2A1 (0.39) | EGFRTP53 | |
| Hydrochloric Acid SCHEMBL5334356 | 0.71 | CSNK2A1 (0.35) | RAB9ANPC1MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070099877-A1 | N-aryl-thienopyrimidin-4-amines and analogs as activators of caspases and inducers of apoptosis and the use thereof | CYTOVIA, INC. (US) | 2007-05-03 | — | — | US | claimed |
| US-20070099877-A1 | N-aryl-thienopyrimidin-4-amines and analogs as activators of caspases and inducers of apoptosis and the use thereof | CYTOVIA, INC. (US) | 2007-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070099877-A1 | N-aryl-thienopyrimidin-4-amines and analogs as activators of caspases and inducers of apoptosis and the use thereof | CASP4, CASP3, API5 | RAB9A 2331/4885NPC1 3693/4885MEN1 1984/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.