Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 13/20 | 0.78 |
| ▸ | HPGD | P15428 | 7/20 | 0.78 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.66 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.66 |
| ▸ | RAB9A | P51151 | 1/20 | 0.66 |
| ▸ | MAPT | P10636 | 2/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.62 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | APEX1 | P27695 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30227915 | 0.90 | ALDH1A1 (0.64) | ALDH1A1HPGDKDM4EHSD17B10RAB9A | |
| SCHEMBL5329981 | 0.81 | ALDH1A1 (0.60) | ALDH1A1HPGDKDM4EHSD17B10RAB9A | |
| SCHEMBL5327950 | 0.80 | ALDH1A1 (0.85) | ALDH1A1HPGDKDM4EHSD17B10MAPT | |
| SCHEMBL30228241 | 0.78 | ALDH1A1 (0.57) | ALDH1A1HPGDKDM4EHSD17B10RAB9A | |
| SCHEMBL30228252 | 0.78 | ALDH1A1 (0.57) | ALDH1A1HPGDKDM4EHSD17B10RAB9A | |
| SCHEMBL21630173 | 0.78 | ALDH1A1 (0.68) | ALDH1A1HPGDKDM4EKMT2AMAPK1 | |
| SCHEMBL13780711 | 0.78 | POLB (0.74) | ALDH1A1HPGDKDM4EHSD17B10SMN1; SMN2 | |
| SCHEMBL25449219 | 0.76 | MAPT (0.77) | ALDH1A1HPGDHSD17B10MAPTSMN1; SMN2 | |
| SCHEMBL21629582 | 0.75 | POLB (0.86) | ALDH1A1HPGDKDM4EHSD17B10RAB9A | |
| SCHEMBL21629540 | 0.75 | ALDH1A1 (1.00) | ALDH1A1HPGDKDM4ERAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007144625-A1 | 2-OXO-2H-CHROMENE COMPOUNDS | ARGENTA DISCOVERY LIMITED (GB) | 2007-12-21 | — | — | WO | claimed |
| WO-2007144625-A1 | 2-OXO-2H-CHROMENE COMPOUNDS | ARGENTA DISCOVERY LIMITED (GB) | 2007-12-21 | — | — | WO | disclosed |