Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.57 |
| ▸ | HPGD | P15428 | 5/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30227915 | 0.89 | ALDH1A1 (0.64) | ALDH1A1HPGDHSD17B10MAPK1KDM4E | |
| SCHEMBL30228252 | 0.86 | ALDH1A1 (0.57) | ALDH1A1HPGDHSD17B10MAPK1KDM4E | |
| SCHEMBL30231646 | 0.84 | ALDH1A1 (0.46) | ALDH1A1HPGDHSD17B10MAPK1KDM4E | |
| SCHEMBL30227919 | 0.82 | ALDH1A1 (0.53) | ALDH1A1HPGDHSD17B10MAPK1KDM4E | |
| SCHEMBL5332450 | 0.78 | ALDH1A1 (0.78) | ALDH1A1HPGDHSD17B10MAPK1KDM4E | |
| SCHEMBL30228279 | 0.76 | ALDH1A1 (0.48) | ALDH1A1HPGDHSD17B10MAPK1KDM4E | |
| SCHEMBL31711159 | 0.76 | ALDH1A1 (0.48) | ALDH1A1HPGDHSD17B10MAPK1KDM4E | |
| SCHEMBL21629598 | 0.74 | ALDH1A1 (0.54) | ALDH1A1HPGDHSD17B10MAPK1KDM4E | |
| SCHEMBL30228362 | 0.74 | ALDH1A1 (0.75) | ALDH1A1HPGDMAPK1MAPTSMN1; SMN2 | |
| SCHEMBL30231670 | 0.72 | ALDH1A1 (0.57) | ALDH1A1HPGDHSD17B10KDM4ERAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023034346-A1 | CHROMEN-2-ONE MODULATORS OF POLRMT | PRETZEL THERAPEUTICS, INC. (US) | 2023-03-09 | — | — | WO | disclosed |