Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.41 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5334625 | 1.00 | L3MBTL1 (0.52) | L3MBTL1KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL5332563 | 0.89 | KDM4E (0.45) | L3MBTL1KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL5339446 | 0.88 | L3MBTL1 (0.49) | L3MBTL1KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL14436660 | 0.84 | L3MBTL1 (0.57) | L3MBTL1KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL5334048 | 0.81 | KDM4E (0.45) | L3MBTL1KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL6099291 | 0.76 | ALDH1A1 (0.37) | KDM4EMEN1KMT2AALDH1A1ALOX15 | |
| SCHEMBL5339851 | 0.74 | KDM4E (0.39) | L3MBTL1KDM4EALDH1A1HPGDMAPT | |
| SCHEMBL16156465 | 0.72 | KDM4E (0.43) | KDM4EALDH1A1HPGDRAB9AMAPT | |
| SCHEMBL1705843 | 0.71 | KDM4E (0.79) | L3MBTL1KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL5334323 | 0.70 | SYK (0.45) | KDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11649228-B2 | Zinc indicators for cellular imaging | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2023-05-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11649228-B2 | Zinc indicators for cellular imaging | IAPP, SLC30A6, SLC30A7 | L3MBTL1 2699/4885KDM4E 4766/4885MEN1 2196/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.