Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 11/20 | 0.49 |
| ▸ | TSHR | P16473 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | HTR7 | P34969 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5331844 | 0.79 | HTR6 (0.56) | HTR6DRD2HTR7 | |
| SCHEMBL5327454 | 0.76 | HTR6 (0.58) | HTR6DRD2HTR2AHTR7 | |
| SCHEMBL5327431 | 0.75 | HTR6 (0.58) | HTR6DRD2HTR7 | |
| SCHEMBL5304701 | 0.73 | HTR6 (0.49) | HTR6 | |
| SCHEMBL5324133 | 0.73 | HTR6 (0.57) | HTR6HTR2A | |
| SCHEMBL13504541 | 0.70 | TSHR (0.48) | HTR6TSHRKDM4EHSD17B10GAA | |
| SCHEMBL5334644 | 0.69 | HTR6 (0.59) | HTR6HTR2A | |
| SCHEMBL13504542 | 0.69 | TSHR (0.49) | HTR6TSHRKDM4EHSD17B10DRD2 | |
| SCHEMBL5328799 | 0.68 | HTR6 (0.56) | HTR6 | |
| Hydrochloric Acid SCHEMBL7437799 | 0.67 | HTR6 (0.78) | HTR6DRD2HTR2AHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007020653-A1 | THIOETHER DERIVATIVES AS FUNCTIONAL 5-HT6 LIGANDS | SUVEN LIFE SCIENCES LIMITED (IN) | 2007-02-22 | — | — | WO | claimed |