Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 12/20 | 0.49 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | FAAH | O00519 | 5/20 | 0.42 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP3 | P08254 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | CTSS | P25774 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14529760 | 0.85 | HSD11B1 (0.61) | HSD11B1FAAH | |
| SCHEMBL5315648 | 0.85 | HSD11B1 (0.61) | HSD11B1FAAH | |
| SCHEMBL14529758 | 0.83 | HSD11B1 (0.46) | HSD11B1FAAHMMP1MMP3MMP13 | |
| SCHEMBL14529610 | 0.82 | HSD11B1 (0.46) | HSD11B1CNR1FAAHMMP1MMP3 | |
| SCHEMBL5316746 | 0.71 | ITGB1 (0.50) | HSD11B1CNR1CNR2 | |
| SCHEMBL5311431 | 0.71 | HSD11B1 (0.51) | HSD11B1CNR1CNR2 | |
| SCHEMBL14529619 | 0.69 | HSD11B1 (0.54) | HSD11B1FAAH | |
| SCHEMBL14530354 | 0.69 | HSD11B1 (0.54) | HSD11B1FAAH | |
| SCHEMBL12640491 | 0.68 | HCRTR1 (0.57) | HSD11B1 | |
| SCHEMBL13602116 | 0.67 | HSD11B1 (0.61) | HSD11B1FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007057768-A2 | SULFONYL DERIVATIVES | PFIZER PRODUCTS INC. (US) | 2007-05-24 | — | — | WO | disclosed |