Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5334239 | 0.90 | GAA (0.60) | GAAMEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL5333893 | 0.89 | GAA (0.58) | GAAMEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL5332292 | 0.88 | GAA (0.58) | GAAMEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL5330985 | 0.84 | TSHR (0.56) | GAAMEN1KMT2AADRB2TSHR | |
| SCHEMBL5329135 | 0.81 | ALDH1A1 (0.65) | GAAMEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL5361725 | 0.78 | ALDH1A1 (0.66) | GAAMEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL29020549 | 0.77 | PDE6D (0.51) | GAAMEN1KMT2ACYP3A4CYP2C19 | |
| SCHEMBL5418863 | 0.77 | ALDH1A1 (0.69) | GAAMEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL5327274 | 0.76 | GAA (0.79) | GAAMEN1KMT2ASMN1; SMN2ADRB2 | |
| SCHEMBL5336137 | 0.74 | KMT2A (0.62) | GAAMEN1KMT2ANPSR1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007047394-A2 | THIOTRIAZOLYL DERIVATIVES | EPIX DELAWARE, INC. (US) | 2007-04-26 | — | — | WO | disclosed |