Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.79 |
| ▸ | MEN1 | O00255 | 4/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 2/20 | 0.59 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 4/20 | 0.53 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5334239 | 0.86 | GAA (0.60) | GAAMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL5329766 | 0.86 | GAA (0.64) | GAAMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL5333893 | 0.85 | GAA (0.58) | GAAMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL5422195 | 0.85 | GAA (0.62) | GAAMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL5335903 | 0.82 | HPGD (0.76) | GAAMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL5332292 | 0.78 | GAA (0.58) | GAAMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL6411001 | 0.77 | HTT (0.67) | GAAMEN1KMT2ATSHRALOX15 | |
| SCHEMBL5338355 | 0.77 | TSHR (0.59) | GAAMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL5330985 | 0.76 | TSHR (0.56) | GAAMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL5332827 | 0.76 | GAA (0.56) | GAAMEN1KMT2AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007047394-A2 | THIOTRIAZOLYL DERIVATIVES | EPIX DELAWARE, INC. (US) | 2007-04-26 | — | — | WO | claimed |
| WO-2007047394-A2 | THIOTRIAZOLYL DERIVATIVES | EPIX DELAWARE, INC. (US) | 2007-04-26 | — | — | WO | disclosed |