Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 19/20 | 0.60 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.47 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | HTR1D | P28221 | 1/20 | 0.46 |
| ▸ | HTR1B | P28222 | 1/20 | 0.46 |
| ▸ | HTR1E | P28566 | 1/20 | 0.46 |
| ▸ | HTR1F | P30939 | 1/20 | 0.46 |
| ▸ | HTR7 | P34969 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5332004 | 0.96 | HTR6 (0.58) | HTR6PTGDRPTGDR2HTR1ADRD2 | |
| SCHEMBL5332687 | 0.94 | HTR6 (0.56) | HTR6PTGDRPTGDR2HTR1ADRD2 | |
| SCHEMBL5331612 | 0.94 | HTR6 (0.56) | HTR6PTGDRPTGDR2HTR1ADRD2 | |
| SCHEMBL5330693 | 0.93 | HTR6 (0.53) | HTR6PTGDRPTGDR2HTR1ADRD2 | |
| SCHEMBL5327800 | 0.92 | HTR6 (0.55) | HTR6HTR1ADRD2HTR1DHTR1B | |
| SCHEMBL5425733 | 0.92 | PTGDR2 (0.58) | HTR6PTGDRPTGDR2 | |
| SCHEMBL5327989 | 0.92 | HTR6 (0.52) | HTR6PTGDRPTGDR2HTR1ADRD2 | |
| SCHEMBL5331879 | 0.89 | HTR6 (0.55) | HTR6PTGDRPTGDR2HTR1ADRD2 | |
| SCHEMBL5326862 | 0.89 | HTR6 (0.49) | HTR6PTGDRPTGDR2HTR1ADRD2 | |
| SCHEMBL5329957 | 0.87 | HTR6 (0.58) | HTR6HTR1ADRD2HTR1DHTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007020653-A1 | THIOETHER DERIVATIVES AS FUNCTIONAL 5-HT6 LIGANDS | SUVEN LIFE SCIENCES LIMITED (IN) | 2007-02-22 | — | — | WO | claimed |
| WO-2007020653-A1 | THIOETHER DERIVATIVES AS FUNCTIONAL 5-HT6 LIGANDS | SUVEN LIFE SCIENCES LIMITED (IN) | 2007-02-22 | — | — | WO | disclosed |