Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 17/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | PPARD | Q03181 | 1/20 | 0.45 |
| ▸ | PPARA | Q07869 | 1/20 | 0.45 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.44 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | HTR1D | P28221 | 1/20 | 0.39 |
| ▸ | HTR1B | P28222 | 1/20 | 0.39 |
| ▸ | HTR1E | P28566 | 1/20 | 0.39 |
| ▸ | HTR1F | P30939 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5333545 | 0.91 | HTR6 (0.41) | HTR6PTGDR2LMNAPOLBSMN1; SMN2 | |
| SCHEMBL5331263 | 0.90 | PTGDR2 (0.44) | HTR6PTGDRPTGDR2 | |
| SCHEMBL5332899 | 0.89 | HTR6 (0.60) | HTR6PTGDRPTGDR2HTR1ADRD2 | |
| SCHEMBL5425733 | 0.88 | PTGDR2 (0.58) | HTR6PTGDRPTGDR2 | |
| SCHEMBL5326887 | 0.87 | HTR6 (0.40) | HTR6PPARGPPARDPPARAPTGDR | |
| SCHEMBL5332687 | 0.86 | HTR6 (0.56) | HTR6PTGDRPTGDR2HTR1ADRD2 | |
| SCHEMBL5327989 | 0.86 | HTR6 (0.52) | HTR6PTGDRPTGDR2HTR1ADRD2 | |
| SCHEMBL5332248 | 0.86 | HTR6 (0.44) | HTR6PTGDRPTGDR2LMNAGAA | |
| SCHEMBL5332004 | 0.85 | HTR6 (0.58) | HTR6PTGDRPTGDR2HTR1ADRD2 | |
| SCHEMBL5330693 | 0.85 | HTR6 (0.53) | HTR6PTGDRPTGDR2HTR1ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007020653-A1 | THIOETHER DERIVATIVES AS FUNCTIONAL 5-HT6 LIGANDS | SUVEN LIFE SCIENCES LIMITED (IN) | 2007-02-22 | — | — | WO | disclosed |