Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | XBP1 | P17861 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5435550 | 0.98 | HPGD (0.42) | GAAALOX15TSHRSMN1; SMN2TP53 | |
| SCHEMBL5417960 | 0.84 | GAA (0.39) | GAAALOX15TSHRSMN1; SMN2TP53 | |
| SCHEMBL1104432 | 0.84 | NPSR1 (0.44) | GAAALOX15TSHRSMN1; SMN2HPGD | |
| SCHEMBL19281546 | 0.79 | HPGD (0.40) | GAATSHRHTTHPGDALDH1A1 | |
| SCHEMBL17725768 | 0.79 | GAA (0.40) | GAATSHRALDH1A1HSD17B10KDM4E | |
| SCHEMBL10011799 | 0.78 | ALDH1A1 (0.51) | GAATSHRHTTHPGDALDH1A1 | |
| SCHEMBL1544543 | 0.77 | GAA (0.45) | GAATSHRSMN1; SMN2HTTHPGD | |
| SCHEMBL5333965 | 0.75 | ALDH1A1 (0.44) | GAATSHRSMN1; SMN2HTTRECQL | |
| SCHEMBL5328179 | 0.75 | ALDH1A1 (0.44) | GAATSHRSMN1; SMN2HTTRECQL | |
| SCHEMBL10012346 | 0.73 | ALDH1A1 (0.50) | GAATSHRSMN1; SMN2HTTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007047394-A2 | THIOTRIAZOLYL DERIVATIVES | EPIX DELAWARE, INC. (US) | 2007-04-26 | — | — | WO | disclosed |