Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | TTR | P02766 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5328179 | 1.00 | ALDH1A1 (0.44) | ALDH1A1TSHRKDM4ELMNAMAPK1 | |
| SCHEMBL5435550 | 0.76 | HPGD (0.42) | ALDH1A1TSHRKDM4ELMNAHPGD | |
| SCHEMBL5417960 | 0.75 | GAA (0.39) | ALDH1A1TSHRKDM4ELMNAHPGD | |
| SCHEMBL5332912 | 0.75 | GAA (0.40) | ALDH1A1TSHRKDM4ELMNAHPGD | |
| SCHEMBL1104432 | 0.75 | NPSR1 (0.44) | ALDH1A1TSHRHPGDKMT2AMEN1 | |
| SCHEMBL10011799 | 0.74 | ALDH1A1 (0.51) | ALDH1A1TSHRKDM4ELMNAMAPK1 | |
| SCHEMBL5331477 | 0.74 | ALDH1A1 (0.58) | ALDH1A1KDM4ELMNAMAPK1HPGD | |
| SCHEMBL5329275 | 0.73 | ALDH1A1 (0.53) | ALDH1A1KDM4ELMNAMAPK1HPGD | |
| SCHEMBL5329256 | 0.73 | ALDH1A1 (0.58) | ALDH1A1TSHRLMNAMAPK1HPGD | |
| SCHEMBL1544495 | 0.72 | SMN1; SMN2 (0.58) | ALDH1A1TSHRKDM4ELMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007047394-A2 | THIOTRIAZOLYL DERIVATIVES | EPIX DELAWARE, INC. (US) | 2007-04-26 | — | — | WO | disclosed |