Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 6/20 | 0.49 |
| ▸ | DRD3 | P35462 | 6/20 | 0.49 |
| ▸ | HTR2A | P28223 | 2/20 | 0.49 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.47 |
| ▸ | CHRM4 | P08173 | 4/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | TGM2 | P21980 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | CCR3 | P51677 | 1/20 | 0.40 |
| ▸ | FNTA | P49354 | 1/20 | 0.40 |
| ▸ | FNTB | P49356 | 1/20 | 0.40 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | HTR1D | P28221 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5315537 | 0.84 | CD274 (0.48) | DRD2DRD3CD274CHRM4CCR3 | |
| SCHEMBL5343476 | 0.83 | MCHR1 (0.49) | CD274 | |
| SCHEMBL5316471 | 0.82 | CD274 (0.56) | CD274CHRM4CCR3HTR1A | |
| SCHEMBL5316139 | 0.81 | CD274 (0.51) | DRD2DRD3CD274CHRM4FAAH | |
| SCHEMBL5316201 | 0.81 | CD274 (0.51) | DRD2DRD3CD274CHRM4CCR3 | |
| SCHEMBL5318392 | 0.80 | CD274 (0.58) | DRD2DRD3CD274CHRM4CCR3 | |
| SCHEMBL5332902 | 0.78 | CD274 (0.45) | DRD2DRD3CD274CHRM4CCR3 | |
| SCHEMBL5317499 | 0.78 | CD274 (0.56) | DRD2DRD3CD274CHRM4CCR3 | |
| SCHEMBL5315942 | 0.78 | CD274 (0.56) | DRD2DRD3CD274CHRM4CCR3 | |
| SCHEMBL5318987 | 0.78 | CD274 (0.56) | DRD2DRD3CD274CHRM4CCR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007069986-A1 | NEW OXABISPIDINE COMPOUNDS FOR THE TREATMENT OF CARDIAC ARRHYTHMIAS | ASTRAZENECA AB (SE) | 2007-06-21 | — | — | WO | claimed |