Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5334816 | 0.80 | KDM4E (0.78) | KDM4EGAASMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL5334125 | 0.77 | KMT2A (0.43) | KDM4EGAASMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL5332024 | 0.76 | SMN1; SMN2 (0.43) | SMN1; SMN2TP53KMT2AMAPTPKM | |
| SCHEMBL5331602 | 0.75 | PGR (0.46) | SMN1; SMN2TP53KMT2AMAPTPKM | |
| SCHEMBL6980347 | 0.75 | KDM4E (1.00) | KDM4EGAASMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL5326569 | 0.74 | MAPK8 (0.53) | SMN1; SMN2HPGDTP53KMT2AMAPT | |
| SCHEMBL5327489 | 0.73 | SMN1; SMN2 (0.40) | SMN1; SMN2TP53KMT2AMAPTPKM | |
| SCHEMBL8480237 | 0.73 | MEN1 (0.73) | KDM4EGAASMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL5332658 | 0.72 | SMN1; SMN2 (0.39) | SMN1; SMN2TP53KMT2AMAPTPKM | |
| SCHEMBL30067741 | 0.69 | KDR (0.52) | GAASMN1; SMN2ALDH1A1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007028789-A1 | QUINAZOLINE DERIVATIVES AS ANTIVIRAL AGENTS | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI SPA (IT) | 2007-03-15 | — | — | WO | claimed |
| WO-2007028789-A1 | QUINAZOLINE DERIVATIVES AS ANTIVIRAL AGENTS | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI SPA (IT) | 2007-03-15 | — | — | WO | disclosed |