Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.73 |
| ▸ | LMNA | P02545 | 2/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.73 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.73 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.69 |
| ▸ | GAA | P10253 | 2/20 | 0.69 |
| ▸ | CA9 | Q16790 | 4/20 | 0.59 |
| ▸ | CA12 | O43570 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | HPGD | P15428 | 3/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 2/20 | 0.56 |
| ▸ | GLA | P06280 | 1/20 | 0.55 |
| ▸ | CMA1 | P23946 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 2/20 | 0.51 |
| ▸ | CA2 | P00918 | 2/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5334816 | 0.91 | KDM4E (0.78) | MEN1LMNAKMT2AL3MBTL1KDM4E | |
| SCHEMBL28738835 | 0.84 | MEN1 (1.00) | MEN1LMNAKMT2AL3MBTL1KDM4E | |
| SCHEMBL9743323 | 0.82 | LMNA (0.60) | MEN1LMNAKMT2AL3MBTL1KDM4E | |
| SCHEMBL6980347 | 0.82 | KDM4E (1.00) | MEN1LMNAKMT2AL3MBTL1KDM4E | |
| SCHEMBL6977596 | 0.81 | KDM4E (0.73) | MEN1LMNAKMT2AL3MBTL1KDM4E | |
| SCHEMBL29326503 | 0.81 | TNKS2 (0.55) | MEN1LMNAKMT2AL3MBTL1KDM4E | |
| SCHEMBL6981446 | 0.80 | KDM4E (0.71) | MEN1LMNAKMT2AL3MBTL1KDM4E | |
| SCHEMBL4216288 | 0.79 | MEN1 (0.60) | MEN1LMNAKMT2AL3MBTL1KDM4E | |
| SCHEMBL8886284 | 0.78 | MEN1 (0.77) | MEN1LMNAKMT2AL3MBTL1KDM4E | |
| SCHEMBL6974482 | 0.78 | KDM4E (0.78) | MEN1LMNAKMT2AL3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5977362-A | Process for the preparation of quinazoline-2,4-diones | BAYER AKTIENGESELLSCHAFT (DE) | 1999-11-02 | — | — | US | disclosed |