Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 12/20 | 0.54 |
| ▸ | FLT1 | P17948 | 10/20 | 0.54 |
| ▸ | FLT4 | P35916 | 10/20 | 0.54 |
| ▸ | VCP | P55072 | 1/20 | 0.48 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.47 |
| ▸ | IMPDH2 | P12268 | 2/20 | 0.44 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5349266 | 0.89 | SIRT7 (0.51) | KDRFLT1FLT4VCPTRPV1 | |
| SCHEMBL5336394 | 0.81 | PRKCQ (0.55) | KDRFLT1FLT4 | |
| SCHEMBL5343623 | 0.80 | KDR (0.54) | KDRFLT1FLT4VCPTRPV1 | |
| SCHEMBL5322052 | 0.74 | TRPV1 (0.75) | KDRFLT1FLT4VCPTRPV1 | |
| SCHEMBL5319980 | 0.73 | IMPDH2 (0.61) | KDRFLT1FLT4VCPIMPDH2 | |
| SCHEMBL5318136 | 0.73 | IMPDH2 (0.61) | KDRFLT1FLT4VCPIMPDH2 | |
| SCHEMBL5318816 | 0.72 | SIRT7 (0.51) | KDRFLT1FLT4VCPTRPV1 | |
| Gw549390X SCHEMBL3295009 | 0.71 | KDR (1.00) | KDRFLT1FLT4VCPIMPDH2 | |
| SCHEMBL5232183 | 0.70 | KDR (0.97) | KDRFLT1FLT4VCPIMPDH2 | |
| SCHEMBL31060643 | 0.70 | KDR (0.97) | KDRFLT1FLT4VCPIMPDH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007076161-A2 | COMPOUNDS WITH THERAPEUTIC ACTIVITY | MYRIAD GENETICS, INC (US) | 2007-07-05 | — | — | WO | claimed |
| WO-2007076161-A2 | COMPOUNDS WITH THERAPEUTIC ACTIVITY | MYRIAD GENETICS, INC (US) | 2007-07-05 | — | — | WO | disclosed |