Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT7 | Q9NRC8 | 1/20 | 0.51 |
| ▸ | TRPV1 | Q8NER1 | 8/20 | 0.50 |
| ▸ | VCP | P55072 | 2/20 | 0.49 |
| ▸ | KDR | P35968 | 5/20 | 0.43 |
| ▸ | FLT1 | P17948 | 4/20 | 0.43 |
| ▸ | FLT4 | P35916 | 4/20 | 0.43 |
| ▸ | NOS1 | P29475 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.39 |
| ▸ | RET | P07949 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5349266 | 0.83 | SIRT7 (0.51) | SIRT7TRPV1VCPKDRFLT1 | |
| SCHEMBL5345073 | 0.80 | RET (0.53) | TRPV1KDRFLT1FLT4RET | |
| SCHEMBL5316979 | 0.76 | TRPV1 (0.74) | SIRT7TRPV1VCPKDRFLT1 | |
| SCHEMBL5336708 | 0.76 | VCP (0.57) | SIRT7TRPV1VCPKDRFLT1 | |
| SCHEMBL5341346 | 0.74 | TRPV1 (0.53) | SIRT7TRPV1VCPKDRFLT1 | |
| SCHEMBL5339016 | 0.74 | VCP (0.58) | SIRT7VCPKDRFLT1FLT4 | |
| SCHEMBL5343891 | 0.74 | VCP (0.58) | SIRT7VCPKDRFLT1FLT4 | |
| SCHEMBL5333207 | 0.72 | KDR (0.54) | TRPV1VCPKDRFLT1FLT4 | |
| SCHEMBL1962130 | 0.68 | TRPV1 (0.77) | SIRT7TRPV1VCPKDRFLT1 | |
| SCHEMBL5319683 | 0.68 | KDR (0.78) | SIRT7TRPV1VCPKDRFLT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007076161-A2 | COMPOUNDS WITH THERAPEUTIC ACTIVITY | MYRIAD GENETICS, INC (US) | 2007-07-05 | — | — | WO | claimed |
| WO-2007076161-A2 | COMPOUNDS WITH THERAPEUTIC ACTIVITY | MYRIAD GENETICS, INC (US) | 2007-07-05 | — | — | WO | disclosed |
| WO-2007076161-A2 | COMPOUNDS WITH THERAPEUTIC ACTIVITY | MYRIAD GENETICS, INC (US) | 2007-07-05 | — | — | WO | disclosed |