Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 3/20 | 0.47 |
| ▸ | CCR3 | P51677 | 5/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.41 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | TNKS | O95271 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5331577 | 0.91 | MPO (0.48) | MPOCCR3POLBDRD2DRD4 | |
| SCHEMBL5332148 | 0.88 | KMT2A (0.44) | CCR3POLBPPARGNR2E3NCOR2 | |
| SCHEMBL5333912 | 0.86 | KDM4E (0.48) | POLBPPARGNR2E3NCOR2ALDH1A1 | |
| SCHEMBL5370125 | 0.85 | MPO (0.53) | MPOPOLBPPARGNR2E3NCOR2 | |
| SCHEMBL5375330 | 0.84 | MPO (0.52) | MPOPOLBPPARGNR2E3NCOR2 | |
| SCHEMBL5370003 | 0.84 | MPO (0.52) | MPOPOLBPPARGNR2E3NCOR2 | |
| SCHEMBL5335593 | 0.80 | MPO (0.46) | MPOPOLBPPARGNR2E3NCOR2 | |
| SCHEMBL946692 | 0.78 | MPO (0.59) | MPOPOLBDRD2DRD4DRD3 | |
| SCHEMBL5334148 | 0.78 | POLB (0.44) | POLBDRD2DRD4DRD3ALDH1A1 | |
| SCHEMBL5332260 | 0.78 | POLB (0.44) | POLBPPARGNR2E3NCOR2DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007046112-A1 | ARYLTHIOETHER TRYPTAMINE DERIVATIVES AS FUNCTIONAL 5-HT6 LIGANDS | SUVEN LIFE SCIENCES INC. (IN) | 2007-04-26 | — | — | WO | disclosed |