Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 3/20 | 0.53 |
| ▸ | TNKS | O95271 | 2/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.39 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | FLT3 | P36888 | 2/20 | 0.37 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5375330 | 0.89 | MPO (0.52) | MPOTNKSDRD2DRD4DRD3 | |
| SCHEMBL5370003 | 0.89 | MPO (0.52) | MPOTNKSDRD2DRD4DRD3 | |
| SCHEMBL5367989 | 0.87 | ALDH1A1 (0.46) | MPOKDM4EALDH1A1POLBPPARG | |
| SCHEMBL5371789 | 0.87 | HSD17B10 (0.46) | MPODRD2DRD4DRD3KDM4E | |
| SCHEMBL5331577 | 0.85 | MPO (0.48) | MPOTNKSDRD2DRD4DRD3 | |
| SCHEMBL5378982 | 0.85 | KDM4E (0.49) | KDM4EALDH1A1HPGDHTR1AHRH4 | |
| SCHEMBL5333420 | 0.85 | MPO (0.47) | MPOTNKSDRD2DRD4DRD3 | |
| SCHEMBL946692 | 0.81 | MPO (0.59) | MPOTNKSDRD2DRD4DRD3 | |
| SCHEMBL5333028 | 0.77 | MPO (0.47) | MPOTNKSDRD2DRD4DRD3 | |
| SCHEMBL5335593 | 0.76 | MPO (0.46) | MPOTNKSDRD2DRD4DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007046112-A1 | ARYLTHIOETHER TRYPTAMINE DERIVATIVES AS FUNCTIONAL 5-HT6 LIGANDS | SUVEN LIFE SCIENCES INC. (IN) | 2007-04-26 | — | — | WO | claimed |